Center for Sight, Fall River, Massachusetts

December 8, 2014

Risk Factors Increase Fuchs Dystrophy Severity

Fuchs’ Endothelial  Corneal Dystrophy is a type of corneal disease that affects the inner most layer of the cornea-the endothelium. Fuchs’ Dystrophy progresses slowly. It can be found in both eyes and is slightly more common in women than men. While it is possible to observe Fuchs’ Dystrophy in people in their 30’s and 40’s, it usually does not compromise vision until people are in their 50’s or 60’s.

The corneal endothelial cells are responsible for pumping water out of the deeper layers of the cornea and helping to maintain the corneal transparency or clarity. While the reason is poorly understood, in Fuchs’ Dystrophy, the endothelial cells die, making the endothelium less efficient in its pumping function. This results in the cornea swelling and distorting vision.

Risk Factors Increase Severity of Fuchs Dystrophy
Researchers reporting in the journal Investigative Ophthalmology and Visual Science studied the several risk factors, including smoking, on the development of advanced Fuchs' EndothelialCorneal Dystrophy (FECD) and on central corneal thickness (CCT)-an indication of corneal swelling and poor corneal health. As predicted, being female increased the odds of developing advanced Fuchs' Endothelial Corneal Dystrophy (FECD) by 34% and smoking increased the odds by 30%. Besides reporting that smoking was associated with an increased risk of developing advanced FECD, diabetes was also associated with increased in corneal thickness-reflecting greater risk of corneal swelling.

If you or someone you know has questions about risk factors that increase the severity of Fuchs Endothelia Corneal Dystrophy (FECD), please feel free to call Center for Sight at 508-730-2020, visit www.center-for-sight.com or www.facebook.com/centerforsightfallriver to schedule an appointment.

Center for Sight is conveniently located at 1565 North Main Street, Suite 406, Fall River, Massachusetts 02720 for patients from Massachusetts or Rhode Island.